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The efficacy and acceptability of antidepressant medications

Mar 1, 2018

A significant study has been published in The Lancet, titled "Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis."  This review included 522 placebo-controlled and head-to-head trials involving 116 477 participants. The authors found that all the antidepressants included in the study were more effective than placebo. They found that some antidepressants had a relatively higher response and lower dropout rate than others, indicating that a balance between efficacy and tolerability is needed to ensure that the benefits of antidepressant medications are maximised.

Go to "Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis."